The Institute headquarters is located in the heart of the city of Mumbai at Matunga. The Institute has four major research divisions namely Mechanical Processing Division (MPD), Quality Evaluation and Improvement Division (QEID), Chemical and Biochemical Processing Division (CBPD) and Transfer of Technology Division (TTD. The ginning training centre (GTC) of CIRCOT located in Nagpur serve the ginning industry by training gin fitters and technicians employed in ginning-pressing units dispersed all over India. In addition to training, this centre offers technical consultancy services to gin manufacturers. There are five more Regional units of institute located at Coimbatore, Guntur, Dharwad, Surat and Sirsa.